PAIP2, 1-127 aa, Human, His-tag, E.coli IBATGP0416 from IBL- America

Description

PAIP2, also known as Poly(A)-binding protein-interacting protein 2, acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. It displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization

Product Specs
ItemPAIP2, 1-127 aa, Human, His-tag, E.coli
CompanyIBL- America
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberIBATGP0416
Molecular Weight17.1 kDa (147aa), confirmed by MALDI-TOF
Purity> 90% by SDS - PAGE
Concentration1 mg/ml (determined by Bradford assay)
FormatLiquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol
Quantity100 µg
Source/Expression SystemE.coli
ApplicationsSDS-PAGE
Conjugate/TagHis
SpeciesHuman
Regulatory StatusFor research use only, not for use in diagnostic procedures
TypeRecombinant Protein
NCBI Full Gene Namepoly(A) binding protein interacting protein 2
NCBI Gene AliasesPAIP-2, PAIP2A
Domain/Region/Terminus1-127 aa
StorageCan be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles